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Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease

Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been instructive in understanding the pathobiology of SCD a...

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Detalles Bibliográficos
Autores principales: Khasabova, Iryna A., Gable, Jacob, Johns, Malcolm, Khasabov, Sergey G., Kalyuzhny, Alexander E., Golovko, Mikhail Y., Golovko, Svetlana A., Kiven, Stacy, Gupta, Kalpna, Seybold, Virginia S., Simone, Donald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973472/
https://www.ncbi.nlm.nih.gov/pubmed/35615929
http://dx.doi.org/10.3324/haematol.2021.280460