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Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease
Sickle cell disease (SCD) is the most common inherited disease. Pain is a key morbidity of SCD and opioids are the main treatment but their side effects emphasize the need for new analgesic approaches. Humanized transgenic mouse models have been instructive in understanding the pathobiology of SCD a...
Autores principales: | Khasabova, Iryna A., Gable, Jacob, Johns, Malcolm, Khasabov, Sergey G., Kalyuzhny, Alexander E., Golovko, Mikhail Y., Golovko, Svetlana A., Kiven, Stacy, Gupta, Kalpna, Seybold, Virginia S., Simone, Donald A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973472/ https://www.ncbi.nlm.nih.gov/pubmed/35615929 http://dx.doi.org/10.3324/haematol.2021.280460 |
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