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APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis

Vascular homeostasis is impaired in various diseases thereby contributing to the progression of their underlying pathologies. The endothelial immediate early gene Apolipoprotein L domain-containing 1 (APOLD1) helps to regulate endothelial function. However, its precise role in endothelial cell biolo...

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Detalles Bibliográficos
Autores principales: Stritt, Simon, Nurden, Paquita, Nurden, Alan T., Schved, Jean-François, Bordet, Jean-Claude, Roux, Maguelonne, Alessi, Marie-Christine, Trégouët, David-Alexandre, Mäkinen, Taija, Giansily-Blaizot, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973481/
https://www.ncbi.nlm.nih.gov/pubmed/35638551
http://dx.doi.org/10.3324/haematol.2022.280816