Variation and impact of polygenic hematologic traits in monogenic sickle cell disease

Several of the complications observed in sickle cell disease (SCD) are influenced by variation in hematologic traits (HT), such as fetal hemoglobin (HbF) level and neutrophil count. Previous large-scale genome-wide association studies carried out in largely healthy individuals have identified thousa...

Descripción completa

Detalles Bibliográficos
Autores principales: Pincez, Thomas, Lo, Ken Sin, d’Orengiani, Anne-Laure Pham Hung d’Alexandry, Garrett, Melanie E., Brugnara, Carlo, Ashley-Koch, Allison E., Telen, Marilyn J., Galactéros, Frédéric, Joly, Philippe, Bartolucci, Pablo, Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Red Cell Biology & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973495/
https://www.ncbi.nlm.nih.gov/pubmed/36226494
http://dx.doi.org/10.3324/haematol.2022.281180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973495/
https://www.ncbi.nlm.nih.gov/pubmed/36226494
http://dx.doi.org/10.3324/haematol.2022.281180

Ejemplares similares