ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts

PURPOSE: The gold standard for managing postoperative ocular fibrosis in glaucoma surgery is the chemotherapeutic mitomycin C (MMC) despite its association with significant adverse effects. This study compares in vitro the antifibrotic efficacy and cytotoxicity of the small-molecule TGFβ1 inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales: Teplitsky, Jack E., Vinokurtseva, Anastasiya, Armstrong, James J., Denstedt, James, Liu, Hong, Hutnik, Cindy M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973532/
https://www.ncbi.nlm.nih.gov/pubmed/36826843
http://dx.doi.org/10.1167/tvst.12.2.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973532/
https://www.ncbi.nlm.nih.gov/pubmed/36826843
http://dx.doi.org/10.1167/tvst.12.2.31

Ejemplares similares