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ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts

PURPOSE: The gold standard for managing postoperative ocular fibrosis in glaucoma surgery is the chemotherapeutic mitomycin C (MMC) despite its association with significant adverse effects. This study compares in vitro the antifibrotic efficacy and cytotoxicity of the small-molecule TGFβ1 inhibitor...

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Detalles Bibliográficos
Autores principales:	Teplitsky, Jack E., Vinokurtseva, Anastasiya, Armstrong, James J., Denstedt, James, Liu, Hong, Hutnik, Cindy M. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973532/ https://www.ncbi.nlm.nih.gov/pubmed/36826843 http://dx.doi.org/10.1167/tvst.12.2.31

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