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Canagliflozin Improves Myocardial Perfusion, Fibrosis, and Function in a Swine Model of Chronic Myocardial Ischemia

BACKGROUND: Sodium‐glucose cotransporter‐2 inhibitors are cardioprotective independent of glucose control, as demonstrated in animal models of acute myocardial ischemia and clinical trials. The functional and molecular mechanisms of these benefits in the setting of chronic myocardial ischemia are po...

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Detalles Bibliográficos
Autores principales: Sabe, Sharif A., Xu, Cynthia M., Sabra, Mohamed, Harris, Dwight Douglas, Malhotra, Akshay, Aboulgheit, Ahmed, Stanley, Madigan, Abid, M. Ruhul, Sellke, Frank W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973570/
https://www.ncbi.nlm.nih.gov/pubmed/36583437
http://dx.doi.org/10.1161/JAHA.122.028623