Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice

BACKGROUND: Cardiomyopathy is a leading health threat in Duchenne muscular dystrophy (DMD). Cytosolic calcium upregulation is implicated in DMD cardiomyopathy. Calcium is primarily removed from the cytosol by the sarcoendoplasmic reticulum calcium ATPase (SERCA). SERCA activity is reduced in DMD. Im...

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Detalles Bibliográficos
Autores principales: Morales, Emily D., Yue, Yongping, Watkins, Thais B., Han, Jin, Pan, Xiufang, Gibson, Aaron M., Hu, Bryan, Brito‐Estrada, Omar, Yao, Gang, Makarewich, Catherine A., Babu, Gopal J., Duan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973626/
https://www.ncbi.nlm.nih.gov/pubmed/36695318
http://dx.doi.org/10.1161/JAHA.122.027480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973626/
https://www.ncbi.nlm.nih.gov/pubmed/36695318
http://dx.doi.org/10.1161/JAHA.122.027480

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