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Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells

Cells of interest can be prepared from somatic cells by forced expression of lineage-specific transcription factors, but it is required to establish a vector-free system for their clinical use. Here, we report a protein-based artificial transcription system for engineering hepatocyte-like cells from...

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Detalles Bibliográficos
Autores principales: Takashina, Tomoki, Matsunaga, Akihiro, Shimizu, Yukiko, Sakuma, Tetsushi, Okamura, Tadashi, Matsuoka, Kunie, Yamamoto, Takashi, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974069/
https://www.ncbi.nlm.nih.gov/pubmed/36848084
http://dx.doi.org/10.1097/HC9.0000000000000051