Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis

Parenteral nutrition (PN) in patients with intestinal failure can lead to cholestasis (PNAC). In a PNAC mouse model, farnesoid X receptor (FXR) agonist (GW4064) treatment alleviated IL-1β-dependent cholestatic liver injury. The objective of this study was to determine whether this hepatic protection...

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Detalles Bibliográficos
Autores principales: Ghosh, Swati, Devereaux, Michael W., Anderson, Aimee L., El Kasmi, *Karim C., Sokol, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974070/
https://www.ncbi.nlm.nih.gov/pubmed/36848082
http://dx.doi.org/10.1097/HC9.0000000000000056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974070/
https://www.ncbi.nlm.nih.gov/pubmed/36848082
http://dx.doi.org/10.1097/HC9.0000000000000056

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