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Cryptic lncRNA-encoded ORFs: A hidden source of regulatory proteins

A majority of the human genome is transcribed into noncoding RNAs, of which long noncoding RNAs (lncRNAs) form a large and heterogeneous fraction. While lncRNAs are mostly noncoding, recent evidence suggests that cryptic translation within some lncRNAs may produce proteins with important regulatory...

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Detalles Bibliográficos
Autores principales: Dutta, Anindya, Li, Hui, Abounader, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974087/
https://www.ncbi.nlm.nih.gov/pubmed/36856112
http://dx.doi.org/10.1172/JCI167271