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Digging deep into cells to find mechanisms of kidney protection by SGLT2 inhibitors

The sodium-glucose cotransporter-2 (SGLT2) is expressed on the luminal side of proximal tubule epithelial cells in the kidney. While pharmacological inhibition of SGLT2 provides kidney protection in diabetic kidney disease (DKD), the molecular mechanisms remain unclear. In this issue of the JCI, Sch...

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Detalles Bibliográficos
Autor principal: Tuttle, Katherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974093/
https://www.ncbi.nlm.nih.gov/pubmed/36856116
http://dx.doi.org/10.1172/JCI167700