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A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain

Microglia, resident macrophages of the CNS, are essential to brain development, homeostasis, and disease. Microglial activation and proliferation are hallmarks of many CNS diseases, including neuropathic pain. However, molecular mechanisms that govern the spinal neuroimmune axis in the setting of ne...

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Detalles Bibliográficos
Autores principales: Hu, Xueming, Du, Lixia, Liu, Shenbin, Lan, Zhou, Zang, Kaikai, Feng, Jing, Zhao, Yonghui, Yang, Xingliang, Xie, Zili, Wang, Peter L., Ver Heul, Aaron M., Chen, Lvyi, Samineni, Vijay K., Wang, Yan-Qing, Lavine, Kory J., Gereau, Robert W., Wu, Gregory F., Hu, Hongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974096/
https://www.ncbi.nlm.nih.gov/pubmed/36701202
http://dx.doi.org/10.1172/JCI161507