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A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain
Microglia, resident macrophages of the CNS, are essential to brain development, homeostasis, and disease. Microglial activation and proliferation are hallmarks of many CNS diseases, including neuropathic pain. However, molecular mechanisms that govern the spinal neuroimmune axis in the setting of ne...
Autores principales: | Hu, Xueming, Du, Lixia, Liu, Shenbin, Lan, Zhou, Zang, Kaikai, Feng, Jing, Zhao, Yonghui, Yang, Xingliang, Xie, Zili, Wang, Peter L., Ver Heul, Aaron M., Chen, Lvyi, Samineni, Vijay K., Wang, Yan-Qing, Lavine, Kory J., Gereau, Robert W., Wu, Gregory F., Hu, Hongzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974096/ https://www.ncbi.nlm.nih.gov/pubmed/36701202 http://dx.doi.org/10.1172/JCI161507 |
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