YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma

BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine (NE) skin cancer caused by severe UV-induced mutations or expression of Merkel cell polyomavirus (MCPyV) large and small T antigens (LT and ST). Despite deep genetic differences between MCPyV-positive and -negative subtypes, cur...

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Detalles Bibliográficos
Autores principales: Frost, Thomas C., Gartin, Ashley K., Liu, Mofei, Cheng, Jingwei, Dharaneeswaran, Harita, Keskin, Derin B., Wu, Catherine J., Giobbie-Hurder, Anita, Thakuria, Manisha, DeCaprio, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974098/
https://www.ncbi.nlm.nih.gov/pubmed/36719743
http://dx.doi.org/10.1172/JCI157171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974098/
https://www.ncbi.nlm.nih.gov/pubmed/36719743
http://dx.doi.org/10.1172/JCI157171

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