Antigen specificity and cross-reactivity drive functionally diverse anti–Aspergillus fumigatus T cell responses in cystic fibrosis

BACKGROUND: The fungus Aspergillus fumigatus causes a variety of clinical phenotypes in patients with cystic fibrosis (pwCF). Th cells orchestrate immune responses against fungi, but the types of A. fumigatus–specific Th cells in pwCF and their contribution to protective immunity or inflammation rem...

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Detalles Bibliográficos
Autores principales: Schwarz, Carsten, Eschenhagen, Patience, Schmidt, Henrijette, Hohnstein, Thordis, Iwert, Christina, Grehn, Claudia, Roehmel, Jobst, Steinke, Eva, Stahl, Mirjam, Lozza, Laura, Tikhonova, Ekaterina, Rosati, Elisa, Stervbo, Ulrik, Babel, Nina, Mainz, Jochen G., Wisplinghoff, Hilmar, Ebel, Frank, Jia, Lei-Jie, Blango, Matthew G., Hortschansky, Peter, Brunke, Sascha, Hube, Bernhard, Brakhage, Axel A., Kniemeyer, Olaf, Scheffold, Alexander, Bacher, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974102/
https://www.ncbi.nlm.nih.gov/pubmed/36701198
http://dx.doi.org/10.1172/JCI161593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974102/
https://www.ncbi.nlm.nih.gov/pubmed/36701198
http://dx.doi.org/10.1172/JCI161593

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