Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score

BACKGROUND: Polygenic risk scores (PRS) hold the promise to refine prognostication in hepatocellular cancer (HCC). The few available HCC PRS include germline risk variants identified among individuals of mostly European ancestry, but data are lacking on the transportability of these PRS in multiethn...

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Detalles Bibliográficos
Autores principales: Thrift, Aaron P., Kanwal, Fasiha, Liu, Yanhong, Khaderi, Saira, Singal, Amit G., Marrero, Jorge A., Loo, Nicole, Asrani, Sumeet K., Luster, Michelle, Al-Sarraj, Abeer, Ning, Jing, Tsavachidis, Spiridon, Gu, Xiangjun, Amos, Christopher I., El-Serag, Hashem B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974109/
https://www.ncbi.nlm.nih.gov/pubmed/36854015
http://dx.doi.org/10.1371/journal.pone.0282309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974109/
https://www.ncbi.nlm.nih.gov/pubmed/36854015
http://dx.doi.org/10.1371/journal.pone.0282309

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