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Host heterogeneity and epistasis explain punctuated evolution of SARS-CoV-2

Identifying drivers of viral diversity is key to understanding the evolutionary as well as epidemiological dynamics of the COVID-19 pandemic. Using rich viral genomic data sets, we show that periods of steadily rising diversity have been punctuated by sudden, enormous increases followed by similarly...

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Detalles Bibliográficos
Autores principales: Nielsen, Bjarke Frost, Saad-Roy, Chadi M., Li, Yimei, Sneppen, Kim, Simonsen, Lone, Viboud, Cécile, Levin, Simon A., Grenfell, Bryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974118/
https://www.ncbi.nlm.nih.gov/pubmed/36791146
http://dx.doi.org/10.1371/journal.pcbi.1010896