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κ-Opioid Receptors Improve Vascular Endothelial Dysfunction in Salt-Sensitive Hypertension via PI3K/Akt/eNOS Signaling Pathway

κ-Opioid receptors (κ-OR) are widely used to regulate the activity of the cardiovascular system. To explore the effect and mechanism of κ-OR on salt-sensitive hypertensive endothelial dysfunction, we used Dah1 rats to construct a rat model of salt-sensitive hypertension on a high-salt (HS) diet. The...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Yang, Hong, Zheng, Qin, Chen, Qiuhong, Li, Xiaohui, Guo, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974251/
https://www.ncbi.nlm.nih.gov/pubmed/36865348
http://dx.doi.org/10.1155/2023/5352959