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Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation

Bupivacaine (BUP) may cause neurotoxic effects after spinal anesthesia. Resveratrol (RSV), a natural agonist of Silent information regulator 1 (SIRT1), protects various tissues and organs from damage by regulating endoplasmic reticulum (ER) stress. The aim of this study is to explore whether RSV cou...

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Detalles Bibliográficos
Autores principales: Luo, Yunpeng, Zhao, Yang, Lai, Jian, Wei, Liling, Zhou, Gang, Yu, Yue, Liu, Jingchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974252/
https://www.ncbi.nlm.nih.gov/pubmed/36865484
http://dx.doi.org/10.1155/2023/1176232