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Nitrogen-Containing Bisphosphonates Downregulate Cathepsin K and Upregulate Annexin V in Osteoclasts Cultured In Vitro

INTRODUCTION: Bisphosphonates are widely used in the treatment of osteoporosis; however, they are associated with the serious adverse event of bisphosphonate‐related osteonecrosis of the jaw (BRONJ). AIM: The aim of this study is to assess the effects of nitrogen-containing bisphosphonates (N-PHs) o...

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Detalles Bibliográficos
Autores principales: Bautista-Carbajal, Arturo, Villanueva-Arriaga, Rosina Eugenia, Páez-Arenas, Araceli, Massó-Rojas, Felipe, Frechero Molina, Nelly, García-López, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974278/
https://www.ncbi.nlm.nih.gov/pubmed/36866025
http://dx.doi.org/10.1155/2023/2960941