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HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier

HIV-1 strains are categorized into one of three neutralization tiers based on the relative ease by which they are neutralized by plasma from HIV-1–infected donors not on antiretroviral therapy; tier-1 strains are particularly sensitive to neutralization while tier-2 and tier-3 strains are increasing...

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Detalles Bibliográficos
Autores principales: Bell, Benjamin N., Bruun, Theodora U. J., Friedland, Natalia, Kim, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974412/
https://www.ncbi.nlm.nih.gov/pubmed/36795752
http://dx.doi.org/10.1073/pnas.2215792120