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Cholesterol-rich domain formation mediated by ZO proteins is essential for tight junction formation

Tight junctions (TJs) are cell-adhesion structures responsible for the epithelial barrier. We reported that accumulation of cholesterol at the apical junctions is required for TJ formation [K. Shigetomi, Y. Ono, T. Inai, J. Ikenouchi, J. Cell Biol. 217, 2373–2381 (2018)]. However, it is unclear how...

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Detalles Bibliográficos
Autores principales: Shigetomi, Kenta, Ono, Yumiko, Matsuzawa, Kenji, Ikenouchi, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974431/
https://www.ncbi.nlm.nih.gov/pubmed/36791108
http://dx.doi.org/10.1073/pnas.2217561120