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Cholesterol-rich domain formation mediated by ZO proteins is essential for tight junction formation
Tight junctions (TJs) are cell-adhesion structures responsible for the epithelial barrier. We reported that accumulation of cholesterol at the apical junctions is required for TJ formation [K. Shigetomi, Y. Ono, T. Inai, J. Ikenouchi, J. Cell Biol. 217, 2373–2381 (2018)]. However, it is unclear how...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974431/ https://www.ncbi.nlm.nih.gov/pubmed/36791108 http://dx.doi.org/10.1073/pnas.2217561120 |