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A cryptic oxidoreductase safeguards oxidative protein folding in Corynebacterium diphtheriae

In many gram-positive Actinobacteria, including Actinomyces oris and Corynebacterium matruchotii, the conserved thiol-disulfide oxidoreductase MdbA that catalyzes oxidative folding of exported proteins is essential for bacterial viability by an unidentified mechanism. Intriguingly, in Corynebacteriu...

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Detalles Bibliográficos
Autores principales: Reardon-Robinson, Melissa E., Nguyen, Minh Tan, Sanchez, Belkys C., Osipiuk, Jerzy, Rückert, Christian, Chang, Chungyu, Chen, Bo, Nagvekar, Rahul, Joachimiak, Andrzej, Tauch, Andreas, Das, Asis, Ton-That, Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974433/
https://www.ncbi.nlm.nih.gov/pubmed/36787356
http://dx.doi.org/10.1073/pnas.2208675120