The influence of NUDT15 variants on 6-mercaptopurine-induced neutropenia in Vietnamese pediatric acute lymphoblastic leukemia

6-Mercaptopurine (6-MP) serves as the backbone of maintenance therapy in acute lymphoblastic leukemia. The nucleoside diphosphate-linked moiety X-type motif 15 genes (NUDT15) affects the metabolism of 6-MP and thiopurine-related neutropenia in the Asian population. This study reports the influence o...

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Detalles Bibliográficos
Autores principales: Nguyen, Mai-Lan, Hoang, Anh Vu, Duong, Bich Tram, Phung, Nguyen The Nguyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974434/
https://www.ncbi.nlm.nih.gov/pubmed/36873097
http://dx.doi.org/10.1016/j.xhgg.2023.100183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974434/
https://www.ncbi.nlm.nih.gov/pubmed/36873097
http://dx.doi.org/10.1016/j.xhgg.2023.100183

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