Cargando…
The influence of NUDT15 variants on 6-mercaptopurine-induced neutropenia in Vietnamese pediatric acute lymphoblastic leukemia
6-Mercaptopurine (6-MP) serves as the backbone of maintenance therapy in acute lymphoblastic leukemia. The nucleoside diphosphate-linked moiety X-type motif 15 genes (NUDT15) affects the metabolism of 6-MP and thiopurine-related neutropenia in the Asian population. This study reports the influence o...
Autores principales: | Nguyen, Mai-Lan, Hoang, Anh Vu, Duong, Bich Tram, Phung, Nguyen The Nguyen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974434/ https://www.ncbi.nlm.nih.gov/pubmed/36873097 http://dx.doi.org/10.1016/j.xhgg.2023.100183 |
Ejemplares similares
-
A Simple, Rapid, and Cost-Effective PCR Procedure for Detection of
NUDT15
Gene Variants in Vietnamese Patients with Acute Lymphoblastic Leukemia
por: Tram, Duong Bich, et al.
Publicado: (2023) -
The Effect of NUDT15, TPMT, APEX1, and ITPA Genetic Variations on Mercaptopurine Treatment of Pediatric Acute Lymphoblastic Leukemia
por: Lee, Jae Min, et al.
Publicado: (2021) -
An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia
por: Tanaka, Yoichi, et al.
Publicado: (2021) -
Effects of TPMT, NUDT15, and ITPA Genetic Variants on 6-Mercaptopurine Toxicity for Pediatric Patients With Acute Lymphoblastic Leukemia in Yunnan of China
por: Mao, Xiaoyan, et al.
Publicado: (2021) -
Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?
por: Zhou, Hong, et al.
Publicado: (2018)