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The RecA-directed recombination pathway of natural transformation initiates at chromosomal replication forks in the pneumococcus

Homologous recombination (HR) is a crucial mechanism of DNA strand exchange that promotes genetic repair and diversity in all kingdoms of life. Bacterial HR is driven by the universal recombinase RecA, assisted in the early steps by dedicated mediators that promote its polymerization on single-stran...

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Detalles Bibliográficos
Autores principales: Johnston, Calum H. G., Hope, Rachel, Soulet, Anne-Lise, Dewailly, Marie, De Lemos, David, Polard, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974461/
https://www.ncbi.nlm.nih.gov/pubmed/36795748
http://dx.doi.org/10.1073/pnas.2213867120