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Spatial organization of lysosomal exocytosis relies on membrane tension gradients

Lysosomal exocytosis is involved in many key cellular processes but its spatiotemporal regulation is poorly known. Using total internal reflection fluorescence microscopy (TIRFM) and spatial statistics, we observed that lysosomal exocytosis is not random at the adhesive part of the plasma membrane o...

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Detalles Bibliográficos
Autores principales: Lachuer, Hugo, Le, Laurent, Lévêque-Fort, Sandrine, Goud, Bruno, Schauer, Kristine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974462/
https://www.ncbi.nlm.nih.gov/pubmed/36800388
http://dx.doi.org/10.1073/pnas.2207425120