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Molecular mechanism and energetics of coupling between substrate binding and product release in the F(1)-ATPase catalytic cycle

F(1)-ATPase is a motor protein that couples the rotation of its rotary [Formula: see text] subunit with ATP synthesis or hydrolysis. Single-molecule experiments indicate that nucleotide binding and release events occur almost simultaneously during the synthesis cycle, allowing the energy gain due to...

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Detalles Bibliográficos
Autores principales: Badocha, Michał, Wieczór, Miłosz, Marciniak, Antoni, Kleist, Cyprian, Grubmüller, Helmut, Czub, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974484/
https://www.ncbi.nlm.nih.gov/pubmed/36780529
http://dx.doi.org/10.1073/pnas.2215650120