Probing coenzyme A homeostasis with semisynthetic biosensors

Coenzyme A (CoA) is one of the central cofactors of metabolism, yet a method for measuring its concentration in living cells is missing. Here we introduce the first biosensor for measuring CoA levels in different organelles of mammalian cells. The semisynthetic biosensor is generated through the spe...

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Detalles Bibliográficos
Autores principales: Xue, Lin, Schnacke, Paul, Frei, Michelle S., Koch, Birgit, Hiblot, Julien, Wombacher, Richard, Fabritz, Sebastian, Johnsson, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974488/
https://www.ncbi.nlm.nih.gov/pubmed/36316571
http://dx.doi.org/10.1038/s41589-022-01172-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974488/
https://www.ncbi.nlm.nih.gov/pubmed/36316571
http://dx.doi.org/10.1038/s41589-022-01172-7

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