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The HP1α protein is mandatory to repress the circadian clock and its output genes during the 12 h period of transcriptional repression

The transcriptional repressions driven by the circadian core clock repressors RevErbα, E4BP4, and CRY1/PER1 involve feedback loops which are mandatory for generating the circadian rhythms. These repressors are known to bind to cognate DNA binding sites, but how their circadian bindings trigger the c...

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Detalles Bibliográficos
Autores principales: Misra, Nisha, Damara, Manohar, Chambon, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974504/
https://www.ncbi.nlm.nih.gov/pubmed/36791098
http://dx.doi.org/10.1073/pnas.2213075120