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Photoactivatable nanoagonists chemically programmed for pharmacokinetic tuning and in situ cancer vaccination

Immunotherapy holds great promise for the treatment of aggressive and metastatic cancers; however, currently available immunotherapeutics, such as immune checkpoint blockade, benefit only a small subset of patients. A photoactivatable toll-like receptor 7/8 (TLR7/8) nanoagonist (PNA) system that imp...

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Detalles Bibliográficos
Autores principales: Wan, Jianqin, Ren, Lulu, Li, Xiaoyan, He, Shasha, Fu, Yang, Xu, Peirong, Meng, Fanchao, Xian, Shiyun, Pu, Kanyi, Wang, Hangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974508/
https://www.ncbi.nlm.nih.gov/pubmed/36787350
http://dx.doi.org/10.1073/pnas.2210385120