ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

Anaplastic lymphoma kinase (ALK) fusion variants in Non-Small Cell Lung Cancer (NSCLC) consist of numerous dimerizing fusion partners. Retrospective investigations suggest that treatment benefit in response to ALK tyrosine kinase inhibitors (TKIs) differs dependent on the fusion variant present in t...

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Detalles Bibliográficos
Autores principales: Chuang, Tzu-Po, Lai, Wei-Yun, Gabre, Jonatan L., Lind, Dan E., Umapathy, Ganesh, Bokhari, Abdulmalik A., Bergman, Bengt, Kristenson, Linnea, Thorén, Fredrik B., Le, Anh, Doebele, Robert C., Van den Eynden, Jimmy, Palmer, Ruth H., Hallberg, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974509/
https://www.ncbi.nlm.nih.gov/pubmed/36791109
http://dx.doi.org/10.1073/pnas.2216479120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974509/
https://www.ncbi.nlm.nih.gov/pubmed/36791109
http://dx.doi.org/10.1073/pnas.2216479120

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