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CPNE1 regulates myogenesis through the PERK-eIF2α pathway mediated by endoplasmic reticulum stress

Sarcopenia is characterized by a progressive reduction in muscle mass or muscle physiological function associated with aging, but the relevant molecular mechanisms are not clear. Here, we identify the role of the myogenesis modifier CPNE1 in sarcopenia. CPNE1 is upregulated in aged skeletal muscles...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Pan, Ling, Zeng, Yuexi, Zhu, Xiaonan, You, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974702/
https://www.ncbi.nlm.nih.gov/pubmed/36525128
http://dx.doi.org/10.1007/s00441-022-03720-y