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TP63 Functions as a Tumor Suppressor Regulated by GAS5/miR-221-3p Signaling Axis in Human Non-Small Cell Lung Cancer Cells

BACKGROUND: Tumor protein p63 (TP63) has been proven to play a role as a tumor suppressor in some human cancers, including non-small cell lung cancer (NSCLC). This study aimed to investigate the mechanism of TP63 and analyze the underlying pathway dysregulating TP63 in NSCLC. METHODS: RT-qPCR and We...

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Detalles Bibliográficos
Autores principales: Shen, Qiming, Wang, Haoyou, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974772/
https://www.ncbi.nlm.nih.gov/pubmed/36873253
http://dx.doi.org/10.2147/CMAR.S387781