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A clustering linear combination method for multiple phenotype association studies based on GWAS summary statistics
There is strong evidence showing that joint analysis of multiple phenotypes in genome-wide association studies (GWAS) can increase statistical power when detecting the association between genetic variants and human complex diseases. We previously developed the Clustering Linear Combination (CLC) met...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975197/ https://www.ncbi.nlm.nih.gov/pubmed/36854754 http://dx.doi.org/10.1038/s41598-023-30415-3 |