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Integrated molecular and clinical analysis of BRAF-mutant glioma in adults

BRAF mutations are a significant driver of disease in pediatric low-grade glioma, but the implications of BRAF alterations on the clinical course and treatment response in adult glioma remain unclear. Here, we characterize a multi-institutional cohort of more than 300 patients (>200 adults) with...

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Detalles Bibliográficos
Autores principales: Schreck, Karisa C., Langat, Pinky, Bhave, Varun M., Li, Taibo, Woodward, Eleanor, Pratilas, Christine A., Eberhart, Charles G., Bi, Wenya Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975216/
https://www.ncbi.nlm.nih.gov/pubmed/36854806
http://dx.doi.org/10.1038/s41698-023-00359-y