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Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the injured b...

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Detalles Bibliográficos
Autores principales: Han, Wei, Meißner, Eva-Maria, Neunteibl, Stefanie, Günther, Madeline, Kahnt, Jörg, Dolga, Amalia, Xie, Cuicui, Plesnila, Nikolaus, Zhu, Changlian, Blomgren, Klas, Culmsee, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975220/
https://www.ncbi.nlm.nih.gov/pubmed/36854658
http://dx.doi.org/10.1038/s41419-023-05698-z