Cargando…

Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the injured b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Wei, Meißner, Eva-Maria, Neunteibl, Stefanie, Günther, Madeline, Kahnt, Jörg, Dolga, Amalia, Xie, Cuicui, Plesnila, Nikolaus, Zhu, Changlian, Blomgren, Klas, Culmsee, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975220/ https://www.ncbi.nlm.nih.gov/pubmed/36854658 http://dx.doi.org/10.1038/s41419-023-05698-z

Ejemplares similares

Correction: Dying transplanted neural stem cells mediate survival bystander effects in the injured brain
por: Han, Wei, et al.
Publicado: (2023)

Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain
por: Zhou, Kai, et al.
Publicado: (2017)

Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons
por: Dolga, Amalia M., et al.
Publicado: (2012)

One protein, different cell fate: the differential outcome of depleting GRP75 during oxidative stress in neurons
por: Honrath, Birgit, et al.
Publicado: (2018)

Therapeutic Benefits of Delayed Lithium Administration in the Neonatal Rat after Cerebral Hypoxia-Ischemia
por: Xie, Cuicui, et al.
Publicado: (2014)

Central Application of Aliskiren, a Renin Inhibitor, Improves Outcome After Experimental Stroke Independent of Its Blood Pressure Lowering Effect
por: Panahpour, Hamdollah, et al.
Publicado: (2019)

Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain
por: Wang, Yafeng, et al.
Publicado: (2017)

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures
por: Richter, Maren, et al.
Publicado: (2020)

Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress
por: Doti, N, et al.
Publicado: (2014)

Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells
por: Honrath, Birgit, et al.
Publicado: (2017)

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
por: Dolga, A M, et al.
Publicado: (2014)

Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice
por: Sun, Yanyan, et al.
Publicado: (2016)

Selective Neural Deletion of the Atg7 Gene Reduces Irradiation-Induced Cerebellar White Matter Injury in the Juvenile Mouse Brain by Ameliorating Oligodendrocyte Progenitor Cell Loss
por: Wang, Yafeng, et al.
Publicado: (2019)

Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production
por: Ramzan, Rabia, et al.
Publicado: (2022)

Radiation induces progenitor cell death, microglia activation, and blood-brain barrier damage in the juvenile rat cerebellum
por: Zhou, Kai, et al.
Publicado: (2017)

RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury
por: Wehn, Antonia Clarissa, et al.
Publicado: (2021)

Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia
por: Sun, Yanyan, et al.
Publicado: (2012)

α(1)-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity
por: Gold, Maike, et al.
Publicado: (2014)

Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior Deficits
por: Sato, Yoshiaki, et al.
Publicado: (2018)

Dying to help: Fatal bystander rescues in Australian coastal environments
por: Lawes, Jasmin C., et al.
Publicado: (2020)

SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling
por: Honrath, Birgit, et al.
Publicado: (2018)

Cylindromatosis mediates neuronal cell death in vitro and in vivo
por: Ganjam, Goutham K., et al.
Publicado: (2018)

Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia
por: Sun, Yanyan, et al.
Publicado: (2017)

BID links ferroptosis to mitochondrial cell death pathways
por: Neitemeier, Sandra, et al.
Publicado: (2017)

SK-Channel Activation Alters Peripheral Metabolic Pathways in Mice, but Not Lipopolysaccharide-Induced Fever or Inflammation
por: Bredehöft, Janne, et al.
Publicado: (2022)

The Potential Role of Ferroptosis in Neonatal Brain Injury
por: Wu, Yanan, et al.
Publicado: (2019)

K(Ca)2 channels activation prevents [Ca(2+)](i) deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia
por: Dolga, A M, et al.
Publicado: (2011)

Pathophysiological Role of Global Cerebral Ischemia following Subarachnoid Hemorrhage: The Current Experimental Evidence
por: Plesnila, Nikolaus
Publicado: (2013)

Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat Brain
por: Osato, Kazuhiro, et al.
Publicado: (2018)

Caspase inhibition impaired the neural stem/progenitor cell response after cortical ischemia in mice
por: Osman, Ahmed M., et al.
Publicado: (2015)

Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors
por: Neofytou, Christina, et al.
Publicado: (2023)

AIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia–Ischemia Injury
por: Li, Tao, et al.
Publicado: (2022)

Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
por: Ganjam, Goutham K., et al.
Publicado: (2019)

Engraftment of enteric neural progenitor cells into the injured adult brain
por: Belkind-Gerson, Jaime, et al.
Publicado: (2016)

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury
por: Xie, Cuicui, et al.
Publicado: (2016)

Bystander
por: Gorky, Maksim, 1868-1936
Publicado: (1930)

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis
por: Neitemeier, S, et al.
Publicado: (2016)

Interaction of the Psychiatric Risk Gene Cacna1c With Post-weaning Social Isolation or Environmental Enrichment Does Not Affect Brain Mitochondrial Bioenergetics in Rats
por: Michels, Susanne, et al.
Publicado: (2019)

Mitochondrial Cell Death Control in Familial Parkinson Disease
por: Kroemer, Guido, et al.
Publicado: (2007)

Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy
por: Dachs, Gabi U., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_nfn0pue4k7vt9vjv4075nrdom1