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Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer

Notch signaling is a conserved signaling pathway that participates in many aspects of mammary gland development and homeostasis, and has extensively been associated with breast tumorigenesis. Here, to unravel the as yet debated role of Notch3 in breast cancer development, we investigated its express...

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Detalles Bibliográficos
Autores principales: Brahim, Sonia, Negulescu, Ana-Maria, Geneste, Clara, Schott, Thomas, Lin, Shuheng, Morel, Louis-Oscar, Rama, Nicolas, Gadot, Nicolas, Treilleux, Isabelle, Mehlen, Patrick, Meurette, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975231/
https://www.ncbi.nlm.nih.gov/pubmed/36854682
http://dx.doi.org/10.1038/s41419-023-05674-7