Extracellular intersubunit interactions modulate epithelial Na(+) channel gating
Epithelial Na(+) channels (ENaCs) and related channels have large extracellular domains where specific factors interact and induce conformational changes, leading to altered channel activity. However, extracellular structural transitions associated with changes in ENaC activity are not well defined....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975279/ https://www.ncbi.nlm.nih.gov/pubmed/36649907 http://dx.doi.org/10.1016/j.jbc.2023.102914 |