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Extracellular intersubunit interactions modulate epithelial Na(+) channel gating

Epithelial Na(+) channels (ENaCs) and related channels have large extracellular domains where specific factors interact and induce conformational changes, leading to altered channel activity. However, extracellular structural transitions associated with changes in ENaC activity are not well defined....

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Detalles Bibliográficos
Autores principales:	Zhang, Lei, Wang, Xueqi, Chen, Jingxin, Sheng, Shaohu, Kleyman, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975279/ https://www.ncbi.nlm.nih.gov/pubmed/36649907 http://dx.doi.org/10.1016/j.jbc.2023.102914

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