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Pan-cancer molecular subtypes of metastasis reveal distinct and evolving transcriptional programs

Molecular mechanisms underlying cancer metastasis span diverse tissues of origin. Here, we synthesize and collate the transcriptomes of patient-derived xenografts and patient tumor metastases, and these data collectively represent 38 studies and over 3,000 patients and 4,000 tumors. We identify four...

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Detalles Bibliográficos
Autores principales: Zhang, Yiqun, Chen, Fengju, Creighton, Chad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975284/
https://www.ncbi.nlm.nih.gov/pubmed/36731467
http://dx.doi.org/10.1016/j.xcrm.2023.100932