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Ythdf2 promotes pulmonary hypertension by suppressing Hmox1-dependent anti-inflammatory and antioxidant function in alveolar macrophages

Pulmonary hypertension (PH) is a devastating disease characterized by irreversible pulmonary vascular remodeling (PVR) that causes right ventricular failure and death. The early alternative activation of macrophages is a critical event in the development of PVR and PH, but the underlying mechanisms...

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Detalles Bibliográficos
Autores principales: Hu, Li, Yu, Yanfang, Shen, Yueyao, Huang, Huijie, Lin, Donghai, Wang, Kang, Yu, Youjia, Li, Kai, Cao, Yue, Wang, Qiang, Sun, Xiaoxuan, Qiu, Zhibing, Wei, Dong, Shen, Bin, Chen, Jingyu, Fulton, David, Ji, Yong, Wang, Jie, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975317/
https://www.ncbi.nlm.nih.gov/pubmed/36801705
http://dx.doi.org/10.1016/j.redox.2023.102638