SCF‐FBXL8 contributes to liver metastasis and stem‐cell‐like features in colorectal cancer cells by mediating ubiquitination and degradation of TP53

BACKGROUND: FBXL8 is a conserved F‐box protein, belonging to the ubiquitin ligase complex, which promotes the development and progression of tumours. However, the regulation function and mechanism of FBXL8's involvement in colorectal cancer (CRC) remain unclear. METHODS: RT–PCR is used to detec...

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Detalles Bibliográficos
Autores principales: Yao, Jing, Wang, Xin‐Ping, Yang, Jun, Yang, Zhe, Zhang, Zheng‐Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975457/
https://www.ncbi.nlm.nih.gov/pubmed/36855778
http://dx.doi.org/10.1002/ctm2.1208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975457/
https://www.ncbi.nlm.nih.gov/pubmed/36855778
http://dx.doi.org/10.1002/ctm2.1208

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