Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of (AGTR1+)CAFs in intrahepatic cholangiocarcinoma

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal malignancy characterized by massive fibrosis and has ineffective adjuvant therapies. Here, we demonstrate the potential of angiotensin receptor blockers (ARBs) in targeting iCCA. METHODS: Masson's trichrome staining was used...

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Detalles Bibliográficos
Autores principales: Li, Jian‐Hui, Wu, Xiao, Ni, Xuhao, Li, Ya‐Xiong, Xu, Long, Hao, Xiao‐Yi, Zhao, Wei, Zhu, Xiao‐Xu, Yin, Xiao‐Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975461/
https://www.ncbi.nlm.nih.gov/pubmed/36855786
http://dx.doi.org/10.1002/ctm2.1213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975461/
https://www.ncbi.nlm.nih.gov/pubmed/36855786
http://dx.doi.org/10.1002/ctm2.1213

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