Cargando…
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of (AGTR1+)CAFs in intrahepatic cholangiocarcinoma
BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal malignancy characterized by massive fibrosis and has ineffective adjuvant therapies. Here, we demonstrate the potential of angiotensin receptor blockers (ARBs) in targeting iCCA. METHODS: Masson's trichrome staining was used...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975461/ https://www.ncbi.nlm.nih.gov/pubmed/36855786 http://dx.doi.org/10.1002/ctm2.1213 |