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Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of (AGTR1+)CAFs in intrahepatic cholangiocarcinoma
BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly lethal malignancy characterized by massive fibrosis and has ineffective adjuvant therapies. Here, we demonstrate the potential of angiotensin receptor blockers (ARBs) in targeting iCCA. METHODS: Masson's trichrome staining was used...
Autores principales: | Li, Jian‐Hui, Wu, Xiao, Ni, Xuhao, Li, Ya‐Xiong, Xu, Long, Hao, Xiao‐Yi, Zhao, Wei, Zhu, Xiao‐Xu, Yin, Xiao‐Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975461/ https://www.ncbi.nlm.nih.gov/pubmed/36855786 http://dx.doi.org/10.1002/ctm2.1213 |
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