Unveiling the therapeutic potential of cabozantinib-loaded poly D,L-lactic-co-glycolic acid and polysarcosine nanoparticles in inducing apoptosis and cytotoxicity in human HepG2 hepatocellular carcinoma cell lines and in vivo anti-tumor activity in SCID female mice

INTRODUCTION: The study aimed to develop a nano-based drug delivery system for the treatment of hepatocellular carcinoma (HCC), a type of liver cancer that accounts for 90% of all liver malignancies. The study focused on the use of cabozantinib (CNB), a potent multikinase inhibitor that targets the...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Sankha, Parihar, Vipan Kumar, Prajapati, Bhupendra G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975495/
https://www.ncbi.nlm.nih.gov/pubmed/36874145
http://dx.doi.org/10.3389/fonc.2023.1125857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975495/
https://www.ncbi.nlm.nih.gov/pubmed/36874145
http://dx.doi.org/10.3389/fonc.2023.1125857

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